Depression is a common disorder, and though it might seem like we’ve got it figured out, what it is and how to treat it is actually way more complicated than we think. Hosted by: Hank Green ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at https://www.scishowtangents.org ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Adam Brainard, Greg, Alex Hackman. Sam Lutfi, D.A. Noe, الخليفي سلطان, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: https://www.psychiatry.org/psychiatrists/practice/dsm/feedback-and-questions/frequently-asked-questions https://tonic.vice.com/en_us/article/ne7adg/depression-more-numb-than-sad https://www.nimh.nih.gov/health/statistics/major-depression.shtml#part_155720 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309382/ https://www.psychiatry.org/patients-families/depression/what-is-depression https://emedicine.medscape.com/article/286759-clinical#b4 https://pubchem.ncbi.nlm.nih.gov/compound/serotonin#section=Top https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825 https://blogs.sciencemag.org/pipeline/archives/2018/02/12/understanding-antidepressants-or-not https://www.health.harvard.edu/mind-and-mood/what-causes-depression https://www.sciencedirect.com/science/article/pii/S0896627305000735 https://www.nature.com/articles/s41588-018-0090-3?_ga=2.136339376.1417200391.1528329600-148794356.1528329600 https://www.livescience.com/62432-massive-study-depression-genes.html https://www.dovepress.com/neuroprogression-the-hidden-mechanism-of-depression-peer-reviewed-article-NDT https://www.ncbi.nlm.nih.gov/books/NBK361016/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309382/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896866/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229580/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739676/ https://www.nature.com/articles/mp201080 Image Sources: https://www.istockphoto.com/vector/sad-female-character-standing-under-the-rain-overcast-weather-emotions-solitude-gm1126494547-296600035 https://www.istockphoto.com/vector/professional-burnout-young-exhausted-manager-sitting-at-the-office-long-working-day-gm1084925542-291115476 https://commons.wikimedia.org/wiki/File:Serotonin-2D-skeletal.png https://www.istockphoto.com/photo/sad-woman-suffering-from-insomnia-gm901220642-248635152 https://www.istockphoto.com/photo/daily-plans-gm637393058-113695937 https://www.istockphoto.com/vector/amygdala-medical-labeled-vector-illustration-and-scheme-with-response-to-threat-gm1030518600-276098904