Features: Decreased libido Anorgasmia Delayed ejaculation Common cause of nonadherence of selective serotonin reuptake inhibitors (SSRIs) Assessment / management; Rule out sexual dysfunction due to depression, medical conditions, primary sexual disorder, stress/relationship issues, substance abuse Switch to non-SSRI antidepressant: bupropion or mirtazapine Adjunctive therapy with sildenafil or bupropion Dose reduction for patients on high-dose SSRI (monitor for loss of efficacy)