🏈 If you are looking for NFL Week 17 picks and predictions for the Lions vs 49ers Monday Night Football matchup, we have you covered! Our NFL football handicapping experts discuss the opening weekend from a sports betting perspective, sharing their picks and predictions vs. the current odds. #nflpicks #nflpredictions #mondaynightfootball Detroit Lions vs San Francisco 49ers – Week 17 Monday Night Football 📅 Date: Monday, December 30, 2024 ⏰ Kickoff Time: 8:15 PM ET / 5:15 PM PT 📺 How to Watch on TV: ESPN, ESPN Deportes 📍 Location: Levi’s Stadium in Santa Clara, CA Spread & Total: Spread: 49ers +3.5 Total: Over/Under set at 50.5 points Team Twitter Hashtags: Detroit Lions: #OnePride San Francisco 49ers: #FTTB (Faithful to The Bay) Interesting Facts: The Detroit Lions are looking to secure their best regular-season record in years with next week's game against the Vikings determining the #1 seed in the NFC. The San Francisco 49ers are having a down year after multiple injuries to Christian McCaffrey and other running backs on the roster as well Levi’s Stadium provides an exquisite backdrop and has been a fortress for the 49ers in prime-time games. This late-season matchup was thought to be big at the start of the season but San Francisco is out of the playoff race and the Lions have nothing to gain or lose with a win or loss on Monday. The Lions and 49ers last met in the NFC Championship last season with San Francisco coming away with the win. #DetroitLions vs #SanFrancisco49ers 👍 Make sure to SUBSCRIBE to WagerTalk TV; 🔔 CLICK the Bell and never miss an episode! 🏈 More Free NFL Picks: https://www.wagertalk.com/free-sports-picks/NFL 🤑 Free Sports Picks: https://www.wagertalk.com/free-sports-picks 📊 Live Odds: https://www.wagertalk.com/odds 🗞️ News: https://www.wagertalk.com/news 👍 Stay connected with WagerTalk 📺 YouTube: https://wt.buzz/tv 👍 Facebook: https://wt.buzz/fb 🐦 Twitter: https://wt.buzz/tw 📸 Instagram: https://wt.buzz/ig 📰 Reddit: https://wt.buzz/rd ❤️ iHeart Radio: https://wt.buzz/iheart 🍎 Apple Podcasts: https://wt.buzz/ap 📌 Pinterest: https://wt.buzz/pin