Watch the Full Video at https://www.jove.com/v/50638/models-methods-to-evaluate-transport-drug-delivery-systems-across?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022. Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers - a 2 minute Preview of the Experimental Protocol Rasa Ghaffarian, Silvia Muro University of Maryland, Fischell Department of Bioengineering; University of Maryland, Institute for Bioscience and Biotechnology Research; Many therapeutic applications require safe and efficient transport of drug carriers and their cargoes across cellular barriers in the body. This article describes an adaptation of established methods to evaluate the rate and mechanism of transport of drug nanocarriers (NCs) across cellular barriers, such as the gastrointestinal (GI) epithelium. Visit https://www.jove.com?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022 to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: https://www.youtube.com/c/JoVEJournalofVisualizedExperiments