Official Ninja Nerd Website: https://ninjanerd.org You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: https://www.ninjanerd.org/lecture/parkinsons-disease-drugs Ninja Nerds! In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture and be sure to support us below! Table of Contents: 0:00 Lab 0:07 Parkinson’s Disease Medications Introduction 1:20 Basal Ganglia Anatomy 4:23 Direct vs. Indirect Pathway 18:23 Pathophysiology of Parkinson’s Disease 21:26 Drug Classes for Parkinson’s Disease 24:36 Mechanism of Action 38:51 L-Dopa + Carbidopa 1:00:22 Dopamine Agonists 1:06:08 COMT-Inhibitors 1:11:39 MAO-B-Inhibitors 1:20:12 Amantadine 1:27:10 Anticholinergics 1:31:18 PD Medications - Practice Problems 1:36:13 Comment, Like, SUBSCRIBE! Supplemental Lectures: Basal Ganglia - https://youtu.be/hxvep2Y8ShI Pharmacology Source: Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition. Join this channel to get access to perks: https://www.youtube.com/channel/UC6QYFutt9cluQ3uSM963_KQ/join APPAREL | https://shop.ninjanerd.org https://www.amazon.com/s?k=ninja+nerd&ref=nb_sb_noss_2 PODCAST | Apple Podcast: https://podcasts.apple.com/us/podcast/ninja-nerd/id1611469997 Spotify: https://open.spotify.com/show/2ZDXoakATwCgkRH3EpCZYu?si=922326f893f4437e Google Podcast: https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5idXp6c3Byb3V0LmNvbS8xOTQ1NjU1LnJzcw== DONATE PAYPAL | https://www.paypal.com/paypalme/ninjanerdscience SOCIAL MEDIA FACEBOOK | https://www.facebook.com/NinjaNerdlectures INSTAGRAM | https://www.instagram.com/ninjanerdlectures TWITTER | https://twitter.com/ninjanerdsci @NinjaNerdSci DISCORD | https://discord.gg/3srTG4dngW #ninjanerd #parkinsonsdisease #pharmacology