Download SpikeFun here: http://www.dimkovic.com Simulation of the mammal thalamocortical system with 2 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 282 million synapses using SpikeFun demo simulator (v0.67) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al. Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.